Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 19190-91-1, name is 5,6-Dibromo-1,2-dihydroacenaphthylene, A new synthetic method of this compound is introduced below., COA of Formula: C12H8Br2
The preparation method of the raw material A (4,5-dibromoacenaphthene) is as follows: In a 1000 mL two-necked flask, 18.72 g (60 mmOl) of 4,5-dibromofluorene and 500 mL of acetic anhydride were added, stirred and heated to 110 C, and a solution of chromium trioxide in acetic anhydride (46.4 g of three) was slowly added dropwise over about two hours. The chromium oxide is dissolved in 300 mL of acetic anhydride). After the completion of the dropwise addition, the temperature was raised to 160 C and the reaction was continued for 30 minutes. After the reaction was completed, the reaction solution was poured into a beaker containing 1000 g of crushed ice, and stirred to dissipate heat, and then 20 mL of concentrated hydrochloric acid was slowly added dropwise, and the mixture was decompressed. After filtration, a yellow solid was obtained, then the residue was recrystallized from acetic acid, and filtered, and then filtered to give a dark brown solid 5.21 g, yield: 25ยท54%.
The synthetic route of 19190-91-1 has been constantly updated, and we look forward to future research findings.
Reference:
Bromide – Wikipedia,
bromide – Wiktionary