Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 626-40-4, name is 3,5-Dibromoaniline, This compound has unique chemical properties. The synthetic route is as follows., Formula: C6H5Br2N
A solution of 3 (0.7 g, 3.83 mmol) in MeOH (10 mL) was treated with 7 (1.0 g, 4 mmol), refluxed for 12 h, and cooled to roomtemperature to afford 8 (1.6 g, 97%), white crystals, mp 169-170C (MeOH), []D20 -66.72 (c 0.069, DMSO). IR spectrum(, cm-1): 3367-3073 (), 1574 (Ar), 1518 (NH), 1176, 1073 (–), 892 (-, -anomer), 668 (-Br). C12H15Br2NO5.1 NMR spectrum (400 MHz, CDCl3, , ppm, J/Hz): 3.1 (2H, m, -3, 5), 3.17 (3, d, J = 5.2, a), 3.24 (2H, m, -2, 4),3.40-3.65 (1H, ddd, J = 11.8, 5.8, 1.9, H-1), 4.18 (1H, q, J = 5.2, aOH), 4.36 (1H, t, J = 8, H-6), 4.52 (1H, t, J = 5.8, 1-OH),4.96, 4.97 (2H, dd, J = 5.3, 5.5, 3, 5-OH), 5.05 (1H, d, J = 4.8, 4-OH), 6.86 (2H, d, J = 7.6, H-8, 12), 6.89 (1H, d, J = 7.8, NH),6.95 (1H, t, J = 1.6, -10). 13C NMR spectrum (100 MHz, CDCl3, , ppm): 49.1 (a), 61.3 (t, -1), 70.7 (d, -3), 73.5 (d,-5), 77.8 (d, -4), 77.9 (d, -2), 84.5 (d, -6), 115.1 (d, -8, d, -12), 121.5 (d, -10), 123.1 (s, -9, s, -11), 150.7 (s, -7).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 626-40-4.
Reference:
Article; Makaev; Pogrebnoi; Chemistry of Natural Compounds; vol. 52; 1; (2016); p. 86 – 89; Khim. Prir. Soedin.; (2015); p. 80 – 83,4;,
Bromide – Wikipedia,
bromide – Wiktionary