Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 10485-09-3, name is 2-Bromoindene, This compound has unique chemical properties. The synthetic route is as follows., Formula: C9H7Br
Under an argon atmosphere, in a Schlenk flask,Followed by loading 3mmol of 2-bromoindene (Shanghai Bi Pharmaceutical Technology Co., Ltd.)1.5 mmol of 2,4,6-trimethylphenylboronic acid (Shanghai Bi Pharmaceutical Technology Co., Ltd.),3 mmol% of tetrakistriphenylphosphine palladium, 6 mmol% of S-Phos and 3 mmol of potassium phosphate,A mixture of 20 mL of toluene and 10 mL of water was added to dissolve the reaction. The reaction was carried out at 100 C for 24 hours,After cooling, the reaction mixture was extracted with ethyl acetate, the organic phase was dried over anhydrous sodium sulfate, the organic phase solvent was removed,Column chromatography on petroleum ether (Rf = 0.8) gave 2- (2,4,6-trimethylphenyl) indene,The yield is 90%
According to the analysis of related databases, 10485-09-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; University of Science and Technology of China; Xiao Bin; Zhou Qiaolan; Xu Mengyu; (22 pag.)CN107417723; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary