Synthetic Route of 138526-69-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 138526-69-9, name is 1-Bromo-3,4,5-trifluorobenzene, This compound has unique chemical properties. The synthetic route is as follows.
Set the reflux reaction device, put the stirrer into the reaction flask, Adding 4-pentylbiphenylboronic acid, 1,2-difluoro-4-bromobenzene, catalyst Pd (Pph3) 4, sodium carbonate; Sealing the reaction system, replacing the air in the sealing system into nitrogen; Immediately add isopropanol and water, stir and slowly heat reflux to ensure that the system reacts under nitrogen. After 5 hours, the degree of reaction was measured with TLC.
The chemical industry reduces the impact on the environment during synthesis 1-Bromo-3,4,5-trifluorobenzene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Shenzhen Chao Duowei Optoelectric Zi Co., Ltd.; Shenzhen Mokerui Optoelectric Zi Institute; Zhang Guoxian; Bao Rui; (19 pag.)CN106397288; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary