In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Product Details of 61326-44-1
[0070] Synthesis of tcbpe-F (Ri = F, R2 to R4 = H in Scheme 1): To a 250m1 three-neck flask, tetra-(4-bromo-phenyl)ethylene (tpe-Br, 2.71 g, 4.2 mmol), 3-fluoro-4- (methoxycarbonyl)phenylboronic acid (5.OOg, 25.2 mmol) and Pd(PPh3)4 (0.40g ) were added, then THF (100 mL) and K2C03 aqueous solution (3.OM, 15 mL) were added under nitrogen protection at room temperature. The mixture solution was kept at 90 °C for three days. After cooling to room temperature, the reaction solution was extracted with dichloromethane for three times (100 mL x 3). The organic phase was washed with water, dried with anhydrous magnesium sulfate. The crude mixture was purified by flash chromatography using dichloromethane/methanol (V : V =40: 1) as fluent. The product, tcbpe-F-ester, was obtained as green-yellow solid in 63.3percent yield (2.50 g). ?H NMR (400 MHz, CDC13) t5: 7.90 (t, J= 10.8 Hz), 7.36 (d, 8H,J= 11.2 Hz), 7.28 (m, 8H), 7.12(d, 8H,J= 11.2 Hz), 3.87(s, 12H).
The synthetic route of 61326-44-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; LI, Jing; HU, Zhichao; GONG, Qihan; WO2015/164784; (2015); A1;,
Bromide – Wikipedia,
bromide – Wiktionary