Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, A new synthetic method of this compound is introduced below., Computed Properties of C26H16Br4
General procedure: A mixture of 1-(4-bromophenyl)-1,2,2-triphenylethylene (1) (200 mg, 0.48 mmol) and 4-(2,2-diphenylvinyl)phenylboronic acid (8) (174 mg, 0.58 mmol) were dissolved in toluene (10 mL) under argon atmosphere. Aqueous solution of K2CO3 (2 ml, 2 M), tricaprylylmethyl ammoniumchloride (Aliquat® 336) (3 drops) and Pd(PPh)4 (10 mg) was added to the mixture. The reaction mixture was heated at 90 ºC overnight. After being cooled to room temperature, distilled water (5 mL) was added and extracted with dichloromethane (3×10 mL). Organic layer was dried over anhydrous Na2SO4. The solvent was removed under reduced pressure, the residue was purified using column chromatography (silica gel/ethyl acetate: petroleum ether 5:95) affoarded the compound 10 (240 mg, 85percent) as a white solid.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Jana, Debabrata; Ghorai, Binay K.; Tetrahedron Letters; vol. 53; 50; (2012); p. 6838 – 6842;,
Bromide – Wikipedia,
bromide – Wiktionary