Adding a certain compound to certain chemical reactions, such as: 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 61326-44-1, Product Details of 61326-44-1
Under argon protection,Tetrakis(4-bromophenyl)ethene 210.7 mg, 0.33 mmol) was added to the reaction flask in that order.3,4,5-trifluorobenzeneboronic acid (274.9 mg, 1.56 mmol),Potassium carbonate (135.4 mg, 0.98 mmol),Tetrakis(triphenylphosphine)palladium (20.3 mg, 0.018 mmol),Tetrabutylammonium bromide (12.3 mg, 0.038 mmol),Add 20 mL of toluene and 5 mL of deionized water.The mixture was heated to 100 ° C, reacted for 27 h, and the reaction was monitored by thin layer chromatography.After the system was lowered to 27 ° C, the liquid was separated.The aqueous phase was extracted with dichloromethane (15 mL×3) and the organic phases were combined.Add anhydrous sodium sulfate and filter,The filtrate is concentrated and subjected to thin layer chromatography.The developing agent ratio is dichloromethane: n-hexane (V: V) = 2:1,The bright blue band of the product (observed under a 365 nm UV lamp) is scraped off.After fully crushing, pour into a sand core funnel and rinse with 80 mL of dichloromethane.Evaporate dry solvent,Obtaining a yellow solid is the target product F-TPE,The weight was 169.2 mg, and the yield was 61.02percent.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; University of Jinan; Miao Jinling; Xiong Zhixin; Nie Yong; Zhang Hao; (15 pag.)CN108947766; (2018); A;,
Bromide – Wikipedia,
bromide – Wiktionary