Synthetic Route of 25462-61-7, The chemical industry reduces the impact on the environment during synthesis 25462-61-7, name is 2,5-Dibromobenzene-1,4-diamine, I believe this compound will play a more active role in future production and life.
Under a stream of nitrogen 2,5-dibromobenzene-1 ,4-diamine (53.18 g, 200.0 mmol), phenyl acetylene (40.86 g, 400.0 mmol), Cs2CO3 (260.66 g, 800.0 mmol), [Cu(phen)(PPh3)2]NO3 (33.21 g, 40.0 mmol), were combined and mixed to toluene (2 L) was stirred at 110 C for 24 hours. Put Sodium butoxide (115.32 g, 1200.0 mmol) was stirred for for 2 h at 110 C. After completion of the reaction, and extracted with methylene chloride, it was put into the filter MgSO4. The solvent of the filtered organic layer was purified by column chromatography to Sub 1-1 (39.47 g, yield: 64%) was obtained.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,5-Dibromobenzene-1,4-diamine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Doosan Corporation; Jo, Hung Sang; Son, Hyo Suk; (40 pag.)KR2016/78138; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary