Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 586-61-8, name is 1-Bromo-4-isopropylbenzene, This compound has unique chemical properties. The synthetic route is as follows., name: 1-Bromo-4-isopropylbenzene
Compound 1-3 (5.28 g, 10 mmol) and 4-isopropyl-bromobenzene (4 g, 20 mmol)Add in a three-necked flask and stir to dissolve with 100 ml of anhydrous toluene.Nitrogen protection followed by Pd(dba)2 (575mg, 1mmol)And sodium tert-butoxide (1.93 g, 20 mmol),Then, a solution of 10% of tri-tert-butylphosphine toluene (4.5 ml) was added, and the reaction solution was stirred and refluxed overnight.After the reaction was completed, it was cooled, and the reaction liquid was washed three times with 100 ml of water.The organic phase was dried over anhydrous sodium sulfate and then evaporated to remove solvent.The residue was purified by DCM/PE (1:15).Obtained white solid compound Cl(4.95 g, yield 56%).
According to the analysis of related databases, 586-61-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Guangzhou Huarui Optoelectric Materials Co., Ltd.; Yang Xi; Pan Junyou; Chen Jia; (38 pag.)CN109608342; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary