Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 7051-34-5, name is (Bromomethyl)cyclopropane, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of (Bromomethyl)cyclopropane
THF (200 mL) was added to the reaction flask, Potassium carbonate (11.0 g, 0.08 mol) and 3-hydroxy-4-difluoromethoxybenzaldehyde (10.0 g, 0.053 mol) were added and the mixture was stirred at room temperature for 1 hour. Then, methyl bromocyclopropane (10.8 g, 0.80 mol) was added and TLC Hydroxy-4-difluoromethoxybenzaldehyde was dissolved and the reaction was quenched by addition of water (100 mL) and extracted with dichloromethane. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate and concentrated to give a brown oil 3-cyclopropylmethoxy-4-difluoromethoxybenzaldehyde (10.5 g, yield 82%, purity 93.9%, HPLC chromatogram shown in Figure 3), without purification can be directly used in the next step reaction
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 7051-34-5.
Reference:
Patent; Taicang Enkang Pharmaceutical Technology Co., Ltd.; Wang Xiang; Shang Muhong; Wang Li; Zhang Feng; Yu Su; Gong Yadong; (12 pag.)CN106883118; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary