Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 454-79-5, name is 2-Bromo-5-(trifluoromethyl)aniline, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C7H5BrF3N
Example 239 2-Mercapto-5-trifluoromethyl-benzothiazole (239) In analogy to the procedure of Chaudhuri, N. Synth. Commun. 1996, 26, 20, 3783, O-ethylxanthic acid, potassium salt (Lancaster, 7.5 g, 46.9 mmol) was added to a solution of 2-bromo-5-trifluoromethylphenylamine (Aldrich, 5.0 g, 20.8 mmol) in N,N-dimethylformamide (DMF, 30 mL). The mixture was heated to reflux for 4 hours. After cooling to room temperature, the mixture was poured into ice water and acidified with 2N HCl. The solid product was collected by filtration. Recrystalization from CHCl3/Hexanes gave 239 (4.5 g, 92%) as a white solid. 1H NMR (400 MHz, DMSO-d6) delta 14.00 (s, 1H), 7.94 (d, J=8.1 Hz, 1H), 7.62 (dd, J=8.4, 1.0 Hz, 1H), 7.48 (d, J=1.0 Hz, 1H). MS (M-H) 234.
According to the analysis of related databases, 454-79-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Tularik Inc.; US2003/139390; (2003); A1;,
Bromide – Wikipedia,
bromide – Wiktionary