Reference of 30432-16-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 30432-16-7, name is 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Dissolve p-toluenesulfonamide (39.4g, 0.23mol) and potassium carbonate (202g, 1.45mol) in N,N-dimethylformamide (400mL), add 1,4-dibromo-2,3-bis(bromomethyl)but-2-ene (40g, 0.10mol), react at room temperature for 24 hours. Water (100 mL) was added to quench the reaction, stirred for 10 minutes, filtered, the filter cake was slurried with ethyl acetate (50 mL), filtered, and the filter cake was collected and dried to give the title compound 9b (39 g, yield 93%) as a white solid.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Gu Zheng; Li Jianhao; Wang Weihua; Tan Haoxiong; Liu Jianyu; Zhang Yingjun; (73 pag.)CN111196806; (2020); A;,
Bromide – Wikipedia,
bromide – Wiktionary