Electric Literature of 141215-32-9, A common heterocyclic compound, 141215-32-9, name is 4,7-Dibromobenzo[c][1,2,5]thiadiazole-5,6-diamine, molecular formula is C6H4Br2N4S, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Gas in the flask with argon purged 200mL flask,Added1500mg heterocyclic compound according to Journal (Heterocycles), 1992, Vol. 33, No. 1, p.337-348 method described in the manufacture of 3 (1.54mmol), benzil 325mg (1.54mmol), acetic acid 25mL , the flask was immersed in an oil bath heated to 120 deg.] C, and reacted for 2 hours. Subsequently, the flask was cooled to room temperature (25 deg.] C), the reaction mixture was poured into 300mL of methanol. The solid was recovered by filtration, washed with methanol, and dried under vacuum to give 629mg of the title compound 32 (1.26mmol).
The synthetic route of 141215-32-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Sumitomo Chemical Co.,Ltd; Ken, Yoshimura; Kenichiro, Oya; (111 pag.)CN105601662; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary