Adding a certain compound to certain chemical reactions, such as: 27976-27-8, name is (6-Bromohexyl)benzene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 27976-27-8, Computed Properties of C12H17Br
(1) 2-(4-Benzyloxyphenyl)-5-methyl-1-[4-(6-phenylhexyloxy)-phenyl]-1H-pyrrole A solution of 4-[2-(4-benzyloxyphenyl)-5-methyl-1H-pyrrol-1-yl]phenol (1.50 g, 4.22 mmol), 1-bromo-6-phenylhexane (1.53 g, 6.33 mmol) and potassium carbonate (874 mg, 6.33 mmol) in DMF (15 ml) was stirred at 80 C. for 12 hours. The reaction solution was poured into water and the mixture was extracted with ethyl acetate. The extract was washed with water, dried over magnesium sulfate anhydride and solvent was removed under reduced pressure. The residue was purified by silica gel column chromatography (hexane:ethyl acetate=20:1) to give the object compound as an oily substance. 1.74 g (yield: 79.4%) 1H-NMR (CDCl3) delta; 1.22-1.83 (8H, m), 2.10 (3H, s), 2.63 (2H, t, J=7.4 Hz), 3.94 (2H, t, J=6.2 Hz), 4.98 (2H, s), 6.04 (1H, d, J=3.2 Hz), 6.25 (1H, d, J=3.2 Hz), 6.74-7.42 (18H, m). IR (KBr) cm-1; 1607, 1514, 1289, 1244, 1177, 1026, 835, 750, 698.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (6-Bromohexyl)benzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Matsumoto, Takahiro; Katayama, Nozomi; Mabuchi, Hiroshi; US2003/144338; (2003); A1;,
Bromide – Wikipedia,
bromide – Wiktionary