Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 111-83-1, Name is 1-Bromooctane, SMILES is CCCCCCCCBr, in an article , author is Gupta, Renu D., once mentioned of 111-83-1, Formula: C8H17Br.
Differential effect of surfactants tetra-n-butyl ammonium bromide and N-Cetyl-N, N, N-trimethyl ammonium bromide bound to nano-cellulose on binding and sustained release of some non-steroidal anti-inflammatory drugs
Nano crystalline cellulose (NCC) modified with cationic surfactant CTAB (N-Cetyl-N, N, N-trimethyl ammonium bromide) proved as effective drug delivery excipient for sustained release of non-steroidal anti-inflammatory drugs (NSAIDs). In the present work, our purpose was to study the effect of another cationic surfactant TBAB (tetra-n-butyl ammonium bromide) used to modify NCC on binding and sustained release of hydrophobic NSAIDs. NCC modified TBAB was characterized by FTIR & TGA analysis. TBAB-NSAID interactions have been assessed using CHEM3D. The sustained release character was monitored by time dependent serum protein protecting and time dependent anti-cathepsins activities. The NCC-TBAB exhibited the binding efficiency for NSAIDs in the range of 42-25% depending upon the hydrophobicity of NSAID and released the drug up to 60 min. The research problem added to the existing knowledge of suitable surfactants required to change the hydrophilic nature of NCC to act as carrier for hydrophobic drugs. TBAB surfactant having shorter alkyl chain length exhibited lower binding efficiency and decreased sustain release of drugs as compared to CTAB having longer alkyl chain length. (C) 2020 Published by Elsevier B.V.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 111-83-1, you can contact me at any time and look forward to more communication. Formula: C8H17Br.