Reference of 3296-90-0, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 3296-90-0, Name is Dibromoneopentyl Glycol, SMILES is OCC(CBr)(CBr)CO, belongs to bromides-buliding-blocks compound. In a article, author is Hafidi, Zakaria, introduce new discover of the category.
Aminoalcohol-based surfactants (N-(hydroxyalkyl)-N, N- dimethyl N-alkylammonium bromide): evaluation of antibacterial activity and molecular docking studies against dehydrosqualene synthase enzyme (CrtM)
The present work investigates the antibacterial activity of three quaternary ammoniums surfactants (QACs): (CnEtOH, CnPrOH, C(n)iPrOH, where n = 12 and 14 carbon atoms against three bacterial strains Escherichia coli (E.coli), Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa). Results obtained show that the three compounds present the best antibacterial effect against Gram-positive S. aureus bacteria with Minimal Inhibitory Concentration (MIC) between 0.016 and 0.13 mmol/L. The evaluation of the zones of inhibition (IZ) and the Minimum Inhibitory Concentration (MIC) shows an increase as a function of the lengthening of the carbon chain from 12 to 14 carbon atoms for all inhibitors against three bacterial strains. The location of the OH group shows its influence on the availability of N+ responsible for the electrostatic interactions with bacterial cell walls, which remains a very important step in the QAC mode of action. It has been found interestingly that for the C-12 and C-14 series, the CnEtOH compound exhibits excellent inhibitory activity among the three inhibitors studied against the three bacterial strains. In addition, the theoretical binding mode of the target molecules was evaluated by docking studies against the Dehydrosqualene synthase enzyme (CrtM) (PDB = 3ACX).
Reference of 3296-90-0, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 3296-90-0.