Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 129316-09-2, Name is 1,3-Dibromo-5-(tert-butyl)benzene, molecular formula is C10H12Br2, belongs to bromides-buliding-blocks compound, is a common compound. In a patnet, author is Mil’, E. M., once mentioned the new application about 129316-09-2, Computed Properties of C10H12Br2.
Apoptotic effect of the anphen sodium antioxidant in combination with H2O2 on Lewis carcinoma cells
It was shown by immunoblotting that the introduction of an antitumor antioxidant, sodium 2-carboxy-2-(N-acetylamino)-3-(3,5-di-tert-butyl-4-hydrophenyl)propanoate (anphen sodium), into a suspension of Lewis carcinoma cells induces a sharp decrease in the contents of the monomer and homodimer of the anti-apoptotic Bcl-2 protein. According to fluorescence analysis, the number of apoptotic cells sharply increased 1 h after exposure to anphen sodium; preliminary addition of 5 mu mol L-1 of hydrogen peroxide increased the cell membrane permeability of anphen sodium and the number of apoptotic cells. The onset of apoptosis detected using fluorophores is comparable in time with the start of the decline of the Bcl-2 level. It was assumed that the mechanism of action of anphen sodium may include the interaction of the agent with the hydrophobic (BH3) domain of Bcl-2 family proteins.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 129316-09-2. The above is the message from the blog manager. Computed Properties of C10H12Br2.