Reference of 2623-87-2, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 2623-87-2, Name is 4-Bromobutanoic acid, SMILES is O=C(O)CCCBr, belongs to bromides-buliding-blocks compound. In a article, author is Tang, Jiahao, introduce new discover of the category.
Synthesis of Cyanoalkynes from Alkyne Bromide and CuCN
A direct generation of cyanoalkynes from alkyne bromide and CuCN was reported. Mild reaction conditions were required, using catalytical amount of KI as the additive and DMSO as the solvent under 60 degrees C. GC analysis showed that alkyne iodide may be the intermediate. Both aromatic ethynyl bromides and aliphatic ethynyl bromides were proved to be good substrates. Good isolated yield was also observed in 10 gram scale synthesis. This method has provided an important alternative synthetic route to cyanoalkyne structures.
Reference of 2623-87-2, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 2623-87-2.