Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 393-36-2, name is 4-Bromo-3-(trifluoromethyl)aniline, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 4-Bromo-3-(trifluoromethyl)aniline
Step 3.1: 3′-Chloro-2-trifluoromethyl-biphenyl-4-amine; A mixture of 5-amino-2-bromobenzotrifluoride (Dakwood Products, Inc.) (500 mg, 2.1 mMol), 3-chlorophenylboronic acid (970 mg, 6.2 mMol, 3 equiv) (Aldrich), Pd(PPh3J4 (70 mg, 0.018 mMol, 0.03 equiv), Na2CO3 (2 M solution in H2O, 5 mL, 10 mMol, 4.76 equiv), and toluene (14 mL) is stirred at reflux for 1 h. The reaction mixture is allowed to cool to rt and filtered through a pad of celite, washing the filter cake with CH2CI2 and H2O. The layers are EPO
According to the analysis of related databases, 393-36-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; NOVARTIS AG; NOVARTIS PHARMA GMBH; WO2006/108640; (2006); A1;,
Bromide – Wikipedia,
bromide – Wiktionary