Reference of 4263-52-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4263-52-9, name is Sodium 2-bromoethanesulphonate belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
A mixture of 1-(2,2-diferrocenylpropane) methyl-imidazole (1.68g, 3.42mmol) and sodium 2-bromoethanesulphonate (0.72g, 3.42mmol) were refluxed at 80C for 16h in DMF (50mL). After cooling to room temperature, the reaction mixture was washed with H2O, and partitioned between H2O and CH2Cl2. The combined organic extract was dried (MgSO4) and concentrated. The residue was purified by silica gel (100-200mesh) chromatography to yield 2 (0.68g, 28%) as an orange-yellow solid. M.p. 46-47C. 1H NMR (400MHz, CDCl3): delta 9.22 (d, 1H, J=28.4Hz, NCHN), 7.50 (d, 1H, J=14.4Hz, NCH), 7.07 (d, 1H, J=7.6Hz, NCH), 5.10 (d, 2H, J=60.4Hz, CH2), 4.59 (s, 2H, CH2), 4.35-3.97 (m, 17H, Cp-H), 3.33 (s, 2H, CH2), 1.66-1.42 (m, 6H, CH3). 13C NMR (101MHz, CDCl3): delta 136.53 (N=C), 122.84 (N=C), 120.82 (N=C), 103.35 (N-CH2-Cp), 102.71 (N-CH2), 78.65 (Cp), 78.38 (Cp), 69.75 (Cp), 69.02 (Cp), 68.18 (Cp), 66,94 (Cp), 50.68 (Cp), 49.78 (Cp), 46.62 (CH2), 33.11 (CH3), 30.50 (CH3). MS (ESI) m/z 701.75 [M]+, 622.83 [M-Br]+, 599.08 [M-Br-Na]+, 78.83 [Br]- Cal. 702. IR (KBr cm-1): upsilon 3094 (=C-H), 2973 (C-H), 1640 (C=C), 1562 (C=N), 1447 (S=O), 1357, 1201, 1106, 1042, 1001, 817, 739, 479. HRMS (M-Br-Na)+: calcd 600.0828, obsd 600.0822.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Sodium 2-bromoethanesulphonate, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Su, Zhi-Ming; Ye, Hong-Min; Zhu, Xiao-Xiao; Xie, Li-Li; Bai, Sha; Yuan, Yao-Feng; Journal of Organometallic Chemistry; vol. 750; (2014); p. 162 – 168;,
Bromide – Wikipedia,
bromide – Wiktionary