Synthetic Route of 626-40-4,Some common heterocyclic compound, 626-40-4, name is 3,5-Dibromoaniline, molecular formula is C6H5Br2N, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
The starting material, 3,5-dibromoaniline(125.35 g, 499.6 mmol) to a round bottom flask in CH2Cl2 (2498ml) todissolve after, acetic anhydride (56.10 g, 549.5 mmol) and K2CO3 (82.85 g,599.5 mmol) at room temperature and the mixture It was stirred. Aftercompletion of reaction, then extracted with water and CH2Cl2 and the organiclayer the product was dried with MgSO4 and concentrated to 140.50 g wasobtained (96% yield).
The synthetic route of 626-40-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; DuksanNeoluxCo., Ltd.; Oh, Dae Hwan; Kim, Dae Sung; Lee, Yun Suk; Jo, Hay Min; Jung, Yeong Suk; Choe, Yeon Hee; Kim, Suk Hyun; (69 pag.)KR101535606; (2015); B1;,
Bromide – Wikipedia,
bromide – Wiktionary