Related Products of 201138-91-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 201138-91-2, name is 4,6-Dibromodibenzo[b,d]furan belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
The 80g (245 mmole) of 4,6-dibromo-dibenzofuran been dissolved by heating in a dry flask 500ml of dry THF. The reaction mixture was cooled to -78 . At this temperature was slowly added dropwise 57ml of n-phenyl lithiumDibutyl ether (115 mmol) of 1.9M solution. The batch was stirred for another hour at -73 deg.] C. Then 65g of 2-chloro-4,6-diphenyl-1,3,5-triazine (245 mmol) was dissolved in 150ml of THF and added dropwise at -70 deg.] C. When the addition was complete, the reaction mixture was slowly warmed to room temperature and stirred at room temperature overnight, quenched with water and then evaporated in a rotary evaporator, during which a white solid precipitated. The batch was then cooled to room temperature, filtered off by suction and has precipitated solid was rinsed with methanol. The yield was 40g (84 mmole), corresponding to 34% of the theoretical.
The synthetic route of 4,6-Dibromodibenzo[b,d]furan has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Merck Patent GmbH; Parham, Amir Hossain; Martynova, Irina; Jatsch, Anja; Eberle, Thomas; Kroeber, Jonas Valentin; Pflumm, Christof; (94 pag.)CN105636959; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary