Adding a certain compound to certain chemical reactions, such as: 2044-08-8, name is 1-Bromocyclohex-1-ene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2044-08-8, Recommanded Product: 1-Bromocyclohex-1-ene
Under nitrogen protection, 20 g (0.12 mol) of 1-bromo-1-cyclohexene and 34.7 g (0.14 mol) of pinacol borate were added to the three-necked flask.2.0 g (6 mol%) of triphenylphosphine,2.6 g (3 mol%) of trans-bis(triphenylphosphine)palladium(II) dichloride,Potassium phenolate 24.6 g (0.19 mol) and anhydrous toluene 250 mL.After nitrogen substitution, the reaction was stirred at 50 C for 5 hours.The system was then cooled to room temperature and quenched with water.The reaction mixture was extracted with a benzene solvent and brine.The organic phase was dried over anhydrous magnesium sulfate.The dried mixture was filtered and concentrated under reduced pressure.It can be purified by silica gel column or distillation to obtain 21.9 g (yield: 85%)Cyclohexene-1-boronic acid pinacol ester.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromocyclohex-1-ene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Yurui (Shanghai) Chemical Co., Ltd.; Zheng Xianzhe; (51 pag.)CN109206457; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary