Electric Literature of 3344-70-5, These common heterocyclic compound, 3344-70-5, name is 1,12-Dibromododecane, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: All compounds were prepared according to previously described procedures [16,17]. Briefly, a phenol derivative (0.015 mol) and a dibromoalkane (0.0075 mol) were dissolved in a mixture of ethanol and water (9/1) containing an alkaline hydroxide (0.015 mol). The mixture was heated under microwave irradiation in an Initiator? Biotage oven for 20 min at 120 ¡ãC. After cooling, the precipitate was filtered and thoroughly washed with water, ethanol and ether.
The synthetic route of 3344-70-5 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Cappoen, Davie; Forge, Delphine; Vercammen, Frank; Mathys, Vanessa; Kiass, Mehdi; Roupie, Virginie; Anthonissen, Roel; Verschaeve, Luc; Vanden Eynde, Jean Jacques; Huygen, Kris; European Journal of Medicinal Chemistry; vol. 63; (2013); p. 731 – 738;,
Bromide – Wikipedia,
bromide – Wiktionary