Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5469-19-2, name is 1-Bromo-2,4,5-trimethylbenzene, This compound has unique chemical properties. The synthetic route is as follows., category: bromides-buliding-blocks
Example 2 This example illustrates the preparation of a triarylaminehaving Formula II I, 4′,4″-(diphenylmethylene)bis(N,N-bis(2,4,5- trimethylphenyl)biphenyl-3-amine), Compound 1 . Compound 1 In a dry box, 4′,4″-(diphenylmethylene)dibiphenyl-3-amine (0.95 g,1 .80 mmol), 1 -bromo-2,4,5-trimethylbenzene (1 .52 g, 7.58 mmol), tris(tert- butyl)phosphine (0.029 g, 0.144 mmol) and Pd2(DBA)3 (0.066 g, 0.072 mmol) were combined in round bottom flask and dissolved in 35 ml of dry toluene. The solution was stirred for a minute and followed by sodium tert- butoxide (0.76 g, 7.94 mmol) and 5 ml of dry toluene. A heating mantle was added and the reaction heated to 60C for 18 hour. The reaction mixture was then cooled to room temperature and filtered, washing with chloroform. The solvent was removed by rotary evaporation and the residue was purified further by silica gel column chromatography using a gradient of chloroform in hexanes (0-36%). The product containing fractions were collected and combined. The solvent was removed by rotary evaporation. The residue was crystallized from dichloromethane and ethanol to give 1 .20 g (68%) product as a white powder. 1 H NMR (CDCI3) is consistent with the structure for Compound 1 .
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 5469-19-2.
Reference:
Patent; E. I. DU PONT DE NEMOURS AND COMPANY; WANG, Ying; WU, Weishi; DOBBS, Kerwin, D.; WO2011/49904; (2011); A2;,
Bromide – Wikipedia,
bromide – Wiktionary