In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2576-47-8, name is 2-Bromoethylamine hydrobromide belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Quality Control of 2-Bromoethylamine hydrobromide
A solution of bromoethylamine hydrobromide (4.2 g, 20 mmol) in 10 mL water was treated successively with benzenesulfonyl chloride (2.61 mL, 20 mmol) and a solution of sodium carbonate (6.5 g, 30 mmol) in 20 mL water. The reaction mixture was stirred at ambient temperature for 16h. Diethyl ether and water were added, the two layers were separated and the organic layer was dried (MgSO4) and concentrated to dryness. Purification on a Redisep cartridge using a gradient 0-100 % of DCM/cyclohexane as eluent provided the title compound. Yield: 3.5 g (66%). LC-MS (Method 4): Rt 2.81 min, m/z no molecular ion observed
The synthetic route of 2576-47-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ARGENTA DISCOVERY LTD; WO2008/96128; (2008); A1;,
Bromide – Wikipedia,
bromide – Wiktionary