Sources of common compounds: 1193389-40-0

The synthetic route of 1193389-40-0 has been constantly updated, and we look forward to future research findings.

1193389-40-0, name is 1-(4-Bromophenyl)cyclobutanamine hydrochloride, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 1193389-40-0

Intermediate AN-(1-(4-bromophenyl)cyclobutyl)-4-(difluoromethoxy)benzenesulfonamideTo a solution of 1-(4-bromophenyl)cyclobutanamine, HCl (845 mg, 3.22 mmol) in DMF (10 mL), was added diisopropylethylamine (1.69 mL, 9.66 mmol) and 4-(difluoromethoxy)benzene-1-sulfonyl chloride (0.529 mL, 3.22 mmol). The reaction mixture was then stirred at r.t., overnight. This mixture was then used, as is, in the following experiment.

The synthetic route of 1193389-40-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Bristol-Myers Squibb Company; US2011/207749; (2011); A1;,
Bromide – Wikipedia,
bromide – Wiktionary