Application of 18392-81-9,Some common heterocyclic compound, 18392-81-9, name is 5,6-Dibromobenzo[c][1,2,5]thiadiazole, molecular formula is C6H2Br2N2S, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1. 1 mmol of 5,6-dibromobenzothiadiazole,2 mmol of triphenylamine-4-boronic acid pinacol ester, 0.05 mmol of tetrakis(triphenylphosphine)palladium, 0.1 mmol of tetrabutylammonium bromide, 6 mmol of sodium hydroxide and 10 ml of toluene, reacted at 120 C for 48 h, with water Extract with dichloromethane and combine the organic layers.After drying, the organic solvent is removed, and purified by using a mixed solvent of dichloromethane and petroleum ether as a solvent column chromatography.4,4′-(Benzo[c][1,2,5]thiadiazole-5,6-diyl)bis(N,N-diphenylaniline) was obtained.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 5,6-Dibromobenzo[c][1,2,5]thiadiazole, its application will become more common.
Reference:
Patent; Heilongjiang University; Han Chunmiao; Zhao Bingjie; Xu Hui; (30 pag.)CN110028506; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary