Extended knowledge of 626-39-1

According to the analysis of related databases, 626-39-1, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 626-39-1, name is 1,3,5-Tribromobenzene, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 626-39-1

n-Butyllithium (2.5 mL of a 2.5 mol/l solution in n-hexane,6.3 mmol) was added to a solution of 1,3,5-tribromobenzene (7) (2.00 g, 6.35 mmol) in Et2O (40mL) at -78 C under inert atmosphere. After 10 min, CuCN (282 mg, 3.18 mmol) was added andthe reaction mixture was allowed to warm up to -60 C within 90 min. Nitrobenzene (0.98 mL,9.53 mmol) was then added in one portion and the dark solution stirred while warming toambient temperature (16 h). An aqueous solution of NH3 (12.5% w/w, 80 mL) was slowly addedand the resulting mixture was extracted with MTBE (3 x 50 mL). The combined organic layerswere washed with water (50 mL) and brine (50 mL), dried over MgSO4, filtered and the solventwas removed in vacuum. Further purification was accomplished by column chromatography(SiO2, n-hexane, Rf 0.69). The resulting material was washed with acetone (20 mL) to give theproduct 8 as a colorless solid (722 mg, 1.54 mmol, 48%), mp 190 C (ref.22 190-191 C). 1HNMR (500 MHz, CDCl3): delta 7.70 (t, J 1.7 Hz, 2 H), 7.59 (d, J 1.7 Hz, 4 H) ppm. 13C{1H} NMR(126 MHz, CDCl3): delta 141.8 (2 C), 133.9 (2 CH), 129.0 (4 CH), 123.6 (4 C) ppm. IR (ATR):3103 (w), 3068 (m), 1579 (m), 1541 (s), 1407 (m), 1387 (m), 1098 (m), 1068 (m), 847 (s), 752(s), 672 (m), 653 (m) cm-1. MS (EI, 70 eV), m/z (%): 466 (95) [M+], 308 (25), 150 (25), 84(100). Anal. calcd. for C12H6Br4 (469.80): C 30.68, H 1.29; found C 30.68, H 1.30.

According to the analysis of related databases, 626-39-1, the application of this compound in the production field has become more and more popular.

Reference:
Article; Behler, Florian; Wickleder, Mathias S.; Christoffers, Jens; ARKIVOC; vol. 2015; 2; (2014); p. 64 – 75;,
Bromide – Wikipedia,
bromide – Wiktionary