Related Products of 3344-70-5,Some common heterocyclic compound, 3344-70-5, name is 1,12-Dibromododecane, molecular formula is C12H24Br2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
1.0 g of compound 3,2.63 g of 1,12-dibromododecane,0.43 g of potassium hydroxide and 0.16 g of tetrabutylammonium bromide,Was added to a mixture of 10 ml of dichloromethane and 6.5 ml of water,The mixture was stirred at room temperature under nitrogen for 24 hours,With 30 millilitersWashed twice with water, washed once with 15 ml of saturated brine, the organic layer was separated, dried over anhydrous sodium sulfate,The solvent was removed on a rotary evaporator and purified by chromatography on a 200-300 mesh silica gel column (eluent ethyl acetate / petroleum ether volume ratio1: 30-1: 10) to give 1.19 g of compound 4 as a pale yellow liquid in 90percent yield.
The synthetic route of 3344-70-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guilin University of Technology; Kong, Xiangfei; Dai, Shengping; Yang, Willow; Deng, Sea; Wang, Guixia; (8 pag.)CN106117224; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary