These common heterocyclic compound, 73918-56-6, name is 2-(4-Bromophenyl)ethanamine, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Product Details of 73918-56-6
To a pre-cooled 0 C. solution of 112 (2.0 g, 10 mmol) in THF (10 mL) was added (Boc)2O (2.2 g, 10 mmol) portionwise. The reaction mixture was stirred at room temperature over night. It was concentrated in vacuo to yield 113 (3 g, 100%) as a white solid which was used in the next step without further purification.
The synthetic route of 2-(4-Bromophenyl)ethanamine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Hydra Biosciences; US2007/219222; (2007); A1;,
Bromide – Wikipedia,
bromide – Wiktionary