Related Products of 108-85-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 108-85-0, name is Bromocyclohexane belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
General procedure: Alkyne (1mmol), sodium azide (1.1mmol), organic halide (1mmol), and water (3mL) were placed together in a 10mL round-bottom flask. PS-C22-CuI (40mg, containing 0.6mol% of Cu) was then added to the above solution. The suspension was magnetically stirred for 10h at room temperature. After completion of the reaction as followed by TLC, EtOAc (5mL) was added to the mixture, filtered, and washed with water (2¡Á3mL) and EtOAc (2¡Á3mL). The organic phase was separated, dried (MgSO4), and concentrated in vacuum to give the crude product that was further purified by recrystallization with ethanol/water (3:1 v/v). In the case of triazole 5h, after completion of the reaction, water was evaporated and EtOAc (5mL) was added. The mixture was filtered to separate the catalyst and the filtrate was concentrated under vacuum to obtain the desired product, which was almost pure.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Bromocyclohexane, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Movassagh, Barahman; Rezaei, Nasrin; Tetrahedron; vol. 70; 46; (2014); p. 8885 – 8892;,
Bromide – Wikipedia,
bromide – Wiktionary