Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 68322-84-9, name is 2-Bromo-1-fluoro-4-(trifluoromethyl)benzene, This compound has unique chemical properties. The synthetic route is as follows., Formula: C7H3BrF4
Example 63 3- {2-Ethyl-4- [3-methyl-5- (2-o-tolyloxy-4-trifluoromethyl-phenoxy)-phenoxy]-phenyl}- propionic acid Step A A mixture 3-benzyloxy-5-methyl-phenol (8.50 g, 39.7 mmol), 3-bromo-4- fluorobenzotrifluoride (9.64 g, 39.7 mmol) and 325 mesh potassium carbonate (6.58 g, 47.6 mmol) in dry DMSO (100 mL) is heated to 100 C and stirred for 8 hours under N2. The reaction is cooled and acidified with 1 N HCI. The mixture is then diluted with water and extracted with Et20. The organic layer is dried (Na2S04), and the solvent is removed in vacuo to afford crude product that is absorbed on silica gel and purified by flash chromatography using 9/1 hexanes/ethyl acetate to afford 14.14 g (81%) product. Rf = 0.52 (4/1 hexanes/EtOAc).’H NMR (400 MHz, CDCl3).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 68322-84-9.
Reference:
Patent; ELI LILLY AND COMPANY; WO2005/37763; (2005); A1;,
Bromide – Wikipedia,
bromide – Wiktionary