In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4117-09-3, name is 7-Bromo-1-heptene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 4117-09-3
To a solution of ethyl 2-oxocyclopentane-l -carboxylate (3.56 mL, 26.7 mmol, 1 equiv.) in acetone (62 mL) at r.t. was rapidly added potassium carbonate (8.43 g, 60.4 mmol, 2.25 equiv.) and potassium iodide (1.43 g, 8.55 mmol, 0.32 equiv.). After stirring for 10 min, a solution of 7-bromohept-l-ene (4.23 mL, 26.9 mmol, 1.01 equiv.) in acetone (17 ml) was added and the reaction was refluxed for 23 h. Diethyl ether (100 mL) was added, the mixture was filtered on a Celite pad and the solvent was evaporated. The residue was diluted with ether, washed with water and brine, dried over sodium sulfate, filtered and concentrated in vacuo to afford ethyl l-(hept-6-en-l-yl)-2-oxocyclopentane-l -carboxylate as an oil (6.37 g, 88 % purity, 92 % yield).
The synthetic route of 4117-09-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; FIRMENICH SA; COULOMB, Julien; DEMOLE, Edouard; (29 pag.)WO2020/78892; (2020); A1;,
Bromide – Wikipedia,
bromide – Wiktionary