Application of 10016-52-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 10016-52-1, name is 2,8-Dibromodibenzo[b,d]furan belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
(3) Synthesis of Compound (300) [0266] [0267] Into a three-necked flask, 3.80 g (10.2 mmol) of Compound (300-b), 1.39 g (4.25 mmol) of Compound (291-a), 15 ml of a 2 M aqueous solution of sodium carbonate, 30 ml of 1,2-dimethoxyethane, and 0.368 g (0.425 mmol)) of Pd(PPh3)4 were charged, and the contents were refluxed for 12 h in a nitrogen atmosphere. [0268] After the reaction, the reaction solution was added with 100 ml of methanol and ultrasonically washed for 10 min. The precipitate was separated by filtration and washed with methanol, water, and then hexane. The washed precipitate was dried, dispersed in ethyl acetate for washing, and recrystallized from toluene, to obtain a white solid. The identification was based on the molecular weight measurement by FD/MS, which showed m/e = 654 for the molecular weight of 654. The yield was 1.50 g and the percent yield was 54%.
The synthetic route of 2,8-Dibromodibenzo[b,d]furan has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Idemitsu Kosan Co., Ltd; NAKANO, Yuki; NUMATA, Masaki; NAGASHIMA, Hideaki; EP2711363; (2014); A1;,
Bromide – Wikipedia,
bromide – Wiktionary