In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 55289-36-6 as follows. Recommanded Product: 55289-36-6
N-(3-Bromo-2-methyl-phen l)-2-hydroxyimino-acetamide A mixture of 3-Bromo-2-methyl-phenylamine (15.6 g, 0.084 mol), NH2OH H2S04 (71.25 g, 0.5 mol), cone. HC1 (8.8 mL) in H20 (90 mL) is slowly added to a solution of chloral hydrate (15.2 g, 0.09 mol), Na2S04 (71.25 g ,0.44 mol) in H20 (255 mL) then stirred at 35C for lh, 52 C for 1.5h, 75 C for lh. After the reaction, the mixture is filtered and the solid is dried under vacuum to give product. Yield: 18 g (83%)
According to the analysis of related databases, 55289-36-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ENGELHARDT, Harald; GIANNI, Davide; MANTOULIDIS, Andreas; SMETHURST, Christian; WO2014/154760; (2014); A1;,
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bromide – Wiktionary