4549-33-1, name is 1,9-Dibromononane, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Application In Synthesis of 1,9-Dibromononane
General procedure: A solution of 2 0.5 g (2 mmol) and anhydrous CH3CN (10 ml) was treated with dihalogenid (1 mmol) and heated on a bath at 70-75 C for different time from 10 to 30 h depending on dihalogenide structure. The solvent was removed at reduced pressure. The resulting precipitate was chromatographed over silica gel ((CHCl3+NH4OH)/MeOH eluent, (100:0?0:100)).
The synthetic route of 4549-33-1 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Sokolova, Anastasiya S.; Yarovaya, Olga I.; Shernyukov, Andrey V.; Pokrovsky, Michail A.; Pokrovsky, Andrey G.; Lavrinenko, Valentina A.; Zarubaev, Vladimir V.; Tretiak, Tatiana S.; Anfimov, Pavel M.; Kiselev, Oleg I.; Beklemishev, Anatoly B.; Salakhutdinov, Nariman F.; Bioorganic and Medicinal Chemistry; vol. 21; 21; (2013); p. 6690 – 6698;,
Bromide – Wikipedia,
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