Adding a certain compound to certain chemical reactions, such as: 141474-37-5, name is 2,4-Dibromo-6-fluoroaniline, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 141474-37-5, Recommanded Product: 2,4-Dibromo-6-fluoroaniline
compound 2,4-dibromo-6-fluroaniline (2,4-dibromo-6-fluoroaniline) 40 g (149 mmol),phenylboronic Acid (Phenylboronic acid) 39.9 g (327 mmol),Tetrakis (triphenylphosphine) palladium (0), 8.59 g (7.44 mmol),K2CO3 82 g (595 mmol), Toluene (Toluene) 600 mL, H2O 150 mL Put the nitrogen was replaced. 24 hours of reaction at 100 degree and Distilled water and dichloromethane (MC), and extracted using NaCl. With a rotary evaporator after the organic layer was dried over anhydrous MgSO4After removal of the solvent hexane (Hexane): dichloromethane (MC) = 20: 1 using a column chromatography (columnPurification by chromatography) to obtain 32.9 g of the desired compound 2-3 (85%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2,4-Dibromo-6-fluoroaniline, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Hee Sung Material Co., Ltd; Kim, Ji Hee; Jang, So Hyun; Kim, Yeong Woo; Kim, Hyun Dong; Uhm, Song Jin; Lee, Ju Dong; (50 pag.)KR2016/1508; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary