Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 502496-36-8, name is 3-Bromo-5-fluoro-2-methylaniline, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C7H7BrFN
To a solution of 3-bromo-5-fluoro-2-methyl-phenylamine (470mg) in dioxane (6 mL) was added triethylamine (1.28 mL), palladium acetate (25 mg), 2-dicyclohexylphosphino biphenyl (161mg) and pinacol borane (1.001ml) and the mixture was heated to 8O0C for 4 h. The reaction mixture was cooled, diluted with chloroform, washed with brine, dried (MgSO4) and the solvent removed in vacuo. The residue was purified using flash chromatography to yield 45 (466 mg).
According to the analysis of related databases, 502496-36-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GENENTECH, INC.; F. HOFFMANN – LA ROCHE AG; WO2009/42607; (2009); A1;,
Bromide – Wikipedia,
bromide – Wiktionary