Adding a certain compound to certain chemical reactions, such as: 45762-41-2, name is 4-Bromo-2-ethylaniline, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 45762-41-2, name: 4-Bromo-2-ethylaniline
A solution of 4-bromo-2-ethylaniline (200 mg) in dichloromethane (10 mL) was treated with 1-fluoro-2-isocyanato-4-methylbenzene (151 mg), stirred at room temperature overnight, diluted with hexanes, and filtered. The filter cake provided 227 mg of the desired product. MS (ESI(+)) m/e 351,353 (M+H)+.
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Reference:
Patent; Dai, Yujia; Davidsen, Steven K.; Ericsson, Anna M.; Hartandi, Kresna; Ji, Zhiqin; Michaelides, Michael R.; US2004/235892; (2004); A1;,
Bromide – Wikipedia,
bromide – Wiktionary