Electric Literature of 615-59-8, The chemical industry reduces the impact on the environment during synthesis 615-59-8, name is 1,4-Dibromo-2-methylbenzene, I believe this compound will play a more active role in future production and life.
2,5-dibromotoluene (10 g, 40 mmol)Was dissolved in anhydrous tetrahydrofuran (40 mL). N-Butyllithium (10 g, 160 mmol) was slowly dropped at -78 ¡ã C., and the mixture was stirred for 2 hours and 30 minutes.Dimethylformamide (15.5 mL, 200 mmol) was added thereto, followed by stirring for 1 hour. Then, 3N hydrochloric acid was added, and anhydrous tetrahydrofuran was removed, followed by extraction with chloroform, drying over anhydrous magnesium sulfate, and purification through silica gel (SiO2, n-hexane: ethyl acetate = 5: 1).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dibromo-2-methylbenzene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Korea National University of Transportation Industry Academy Cooperation Foundation; Lee Ji-hun; Choi Yong-seon; Shin Seong-jun; (65 pag.)KR2019/43743; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary