Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 49764-63-8, name is 4,5-Dibromobenzene-1,2-diamine, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C6H6Br2N2
To a solution of methyl (S)-4-(2-(2-formylbenzoyl)-5,5,8a-trimethyl-1,2,3,5,8,8a- hexahydroisoquinolin-6-yl)benzoate (50 mg, 0.113 mmol) and 4,5-dibromobenzene-1,2- diamine (30 mg, 0.113 mmol) in DMF (2 ml) was added sodium metabisulfite (24 mg, 0.124 mmol). The mixture was stirred at 60 C overnight. The mixture was concentrated in vacuo. The residue was partitioned between EtOAc (20 ml) and H2O (20 ml). The separated aqueous layer was extracted with EtOAc (20 ml). The combined organic layers were washed brine (20 ml), dried over Na2S04, and concentrated in vacuo. The crude product was purified by silica gel column eluted with 35 % EtOAc / hexanes to give the desired product (62 mg, 80 %) as a solid. LC/MS m/z 688.10 (M+H)+, 2.91 min (Method 2).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 49764-63-8.
Reference:
Patent; VIIV HEALTHCARE UK (NO.5) LIMITED; CHEN, Jie; MEANWELL, Nicholas A.; REGUEIRO-REN, Alicia; SIT, Sing-Yuen; SWIDORSKI, Jacob; (267 pag.)WO2018/2848; (2018); A1;,
Bromide – Wikipedia,
bromide – Wiktionary