Synthetic Route of 2862-39-7, The chemical industry reduces the impact on the environment during synthesis 2862-39-7, name is 2-Bromo-N,N-dimethylethanamine hydrobromide, I believe this compound will play a more active role in future production and life.
50 ml of N,N-dimethylformamide and 7.37 g of dimethylaminobromoethane hydrobromide were added to the reaction vessel.(0 ¡¤ 0318 mol), adding 5 g of potassium carbonate, stirring at room temperature for 15 min, adding 4.5 g of 2-benzylpyridine (0.0265 mol), heating to 80 C for 5 h, monitoring by TLC, filtering while hot, adding 150 ml of water and 150 ml of filtrate. Extracted with ethyl acetate and extracted with 100 ml of ethyl acetate.The ethyl acetate phases were combined and concentrated to give 6 g of Pheniramine.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Bromo-N,N-dimethylethanamine hydrobromide, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Guangdong Zhongsheng Pharmaceutical Co., Ltd.; Guangdong Xian Qiang Pharmaceutical Co., Ltd.; Tan Zhenyou; Deng Jun; CN108164455; (2018); A;,
Bromide – Wikipedia,
bromide – Wiktionary