In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 18599-22-9 as follows. HPLC of Formula: C4H3BrF4
4-bromo-3,3,4,4-tetrafluoro-1-butene (8.7 g, 42 mmol), anthracene (5.0 g, 28 mmol) and toluene (100 g) were added to a 300 mL pressure-resistant reaction container, and a reaction was conducted at 150 C. for 24 hours. Subsequently, after cooling to room temperature, the resultant was concentrated using a rotary evaporator. Methanol (50 g) was added to the concentrate, followed by stirring. The precipitated solid was subjected to filtration. Then, the residue was dried under reduced pressure, so as to obtain intermediate product 14 (6.0 g, yield=55.6%).
According to the analysis of related databases, 18599-22-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; TOKYO OHKA KOGYO CO., LTD.; ARAI, Masatoshi; MAEHASHI, Takaya; IKEDA, Takuya; (95 pag.)US2018/149973; (2018); A1;,
Bromide – Wikipedia,
bromide – Wiktionary