Adding a certain compound to certain chemical reactions, such as: 2635-13-4, name is 5-Bromobenzo[d][1,3]dioxole, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2635-13-4, Product Details of 2635-13-4
Step 1a. 5-Bromo-6-iodobenzo[d][1,3]dioxole (Compound 0102-1) A solution of 5-bromobenzo[d][1,3]dioxole (10.0 g, 50.0 mmol), anhydrous acetonitrile (150 mL), TFA (11.4 g, 100.0 mmol) and NIS (33.7 g, 150.0 mmol) was stirred at room temperature for 24 h. The solvent was removed under reduce pressure and the crude purified by column chromatography on silica gel (petroleum) to yield the title compound 0107-1 as a white solid (18.5 g, 91%): 1H NMR (DMSO-d6) delta 5.99 (s, 2H), 7.10 (s, 1H), 7.26 (s, 1H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Bromobenzo[d][1,3]dioxole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Cai, Xiong; Qian, Changgeng; US2010/184801; (2010); A1;,
Bromide – Wikipedia,
bromide – Wiktionary