Synthetic Route of 7051-34-5, These common heterocyclic compound, 7051-34-5, name is (Bromomethyl)cyclopropane, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Step 5; An ice water bath cooled solution of L-cysteine in IN sodium hydroxide (740 ml) and dioxane (740 ml) was treated with bromomethylcyclopropane (50 g, 370 mmol). The reaction mixture was allowed to warm to room temperature and stirred for 16 h. Dioxane was removed under reduced pressure and the resulting aqueous solution was adjusted to pH 6 with 6N HCl and placed in a refrigerator for 20 h. The product was collected by vacuum filtration, washed with hexanes and lyophilized to give 2(i?)-amino-3-cycloprorhoylmethylsulfanylpropionic acid (57.28 g) EPO
The synthetic route of 7051-34-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; AXYS PHARMACEUTICALS, INC.; WO2006/60494; (2006); A1;,
Bromide – Wikipedia,
bromide – Wiktionary