Reference of 4101-68-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4101-68-2, name is 1,10-Dibromodecan belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
1,10-Bisazidodecane NaN3 (1.30 g, 20.0 mmol) was suspended in a solution of 1,10-dibromodecane (2.42 g, 10.0 mmol) in dry dimethylformamide (15 mL). After stirring for 12 h at 60 C. water (15 mL) was added and the mixture was extracted with diethyl ether (3*100 mL). The organic layer was washed with water (3*50 mL), dried over Na2SO4 and evaporated. The crude product was purified by chromatography on silica gel (0%?20% ethyl acetate in cyclohexane). Yield: 6.82 mmol, 68% yellowish oil. 1H: [300 MHz, CDCl3] delta=1.30-1.54 (m, 12H), 1.51-1.68 (m, 4H), 3.26-3.35 (m, 4H) ppm. HRMS: [C10H20N6] m/z cal. [M+H]+=225.1822 m/z found [M+H]+=225.1821.
The synthetic route of 1,10-Dibromodecan has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Arenz, Christoph; Davies, Brian Patrick; Neubacher, Saskia; Klemm, Claudine Mercedes; US2009/92980; (2009); A1;,
Bromide – Wikipedia,
bromide – Wiktionary