Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 586-61-8, name is 1-Bromo-4-isopropylbenzene, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C9H11Br
A mixture of 30.0 g (0.20 mol) of 2-FORMYLPHENYLBORONIC acid, 43.8 g (0. 22 MOL) of 4-bromoisopropylbenzene, 91.0 g (0.60 mol) of caesium fluoride and 6.9 g (0.0060 mol) of tetrakis (triphenylphosphine) palladium (0) in 700 ml of 1,2-dimethoxyethane is refluxed under a nitrogen atmosphere for 3 hours. After cooling, 1.5 1 of diethyl ether and 1 1 of water are added to the reaction medium and the organic phase is separated out, dried over sodium sulfate and concen- trated. The oily residue obtained is purified by chromatography on a column of silica (eluent : 30/1 hexane/ethyl acetate) to give 25.3 g (56.4%) of a pale yellow oil corresponding to the title compound. NMR: (CDCI3) 8 (PPM) : 1.31 (6 H, d, J = 7 Hz); 2.99 (1 H, sept, J = 7 Hz); 7.26-7. 39 (4 H, m); 7.41-7. 53 (2 H, m); 7.54-7. 69 (1 H, m); 7.93-8. 13 (1 H, m); 10. 01 (1 H, s). I R : v (C =0) : 1694 CM~
According to the analysis of related databases, 586-61-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK PATENT GMBH; WO2004/37806; (2004); A1;,
Bromide – Wikipedia,
bromide – Wiktionary