Some common heterocyclic compound, 114078-88-5, name is 5-Bromo-1,2,3-triazine, molecular formula is C3H2BrN3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: 5-Bromo-1,2,3-triazine
Weigh 5-bromo-1,2,3-triazine (4.4g, 27.5mmol) was dissolved in chloroform (40 mL), and cooled to 0 deg.] C, was added 1-(cyclopentan-1-en-1-yl)pyrrolidine with stirring -1 After the addition, the reaction mixture was stirred at 0 C for 5 minutes, and raised to 45 C for 45 minutes. The crude product was purified by column chromatography on silica gel (petroleum ether: ethyl acetate = 5: 1 (1: 1) ) to give the title compound (1.86g, yield 34.2%).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 114078-88-5, its application will become more common.
Reference:
Patent; XuanZhu Pharma Co.,Ltd.; Wu, Yongqian; (49 pag.)CN105884752; (2016); A;,
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bromide – Wiktionary