Adding a certain compound to certain chemical reactions, such as: 2270-59-9, name is 5-Bromo-2-methylpent-2-ene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2270-59-9, Safety of 5-Bromo-2-methylpent-2-ene
Potassium carbonate (49 mg), potassium iodide (29.4 mg) and 5-bromo-2-methyl- 2-pentene (35.3 muL) was added to a solution of Compound No. 12 (62 mg) in acetonitrile (3 mL). The mixture was stirred at 800C for 5 hours and subsequently at room temperature overnight. The mixture was concentrated under reduced pressure and the residue thus obtained was partitioned between dichloromethane and water. The separated organic layer was washed with water and brine, dried over anhydrous sodium sulphate and concentrated under reduced pressure. The residue thus obtained was purified by preparative column chromatography to yield the title compound. Yield: 27mg1H NMR (CDCl3):delta 7.43-7.33 (1OH, m), 5.07-5.04 (IH, m), 3.65-3.47 (IH, m), 3.15-2.05 (13H, m), 21.78-1.73 (6H, m), 1.33-1.1 (4H, m).Mass (m/z): 433 (M++.).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Bromo-2-methylpent-2-ene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; RANBAXY LABORATORIES LIMITED; WO2007/39884; (2007); A1;,
Bromide – Wikipedia,
bromide – Wiktionary